Özet:

Anaplastic thyroid carcinoma (ATC) is a rare, fatal disease without effective systemic treatment. ATC is usually shown with local symptoms that cause dysphagia, dysphonia or sound discomfort, stridor and dyspnea symptoms, depending on the mass effect of the ozofagus and trachea, along with the rapidly growing thyroid mass. A 56-year-old woman was sent to the hospital due to swelling in her neck. In the thyroid, a hard, unmovable tumor and a unmovable lymphatic nod was detected on the left side of the neck. The patient was given a 75 mg / m2 / day cisplatin as a first-stage treatment, a 60 mg / m2 / day dosorubin per 21 days, a 6 cubic chemotherapy regime per 21 days. After 6 chemotherapy, the F18-FDG-PET has not been massally detected. Radioactive remission was provided. The patient was operated two weeks later. Total thyroidectomy, bilateral central and left-modified radical cervical lymph nod disection were performed. A complete R0 recession was provided surgically. The best outcomes in terms of endurance are obtained by a multidisciplinary treatment that combines surgery, external radiotherapy and chemotherapy. But despite multidisciplinary therapy, the answers to treatment are not hopeful. First stage neadjuvan chemotherapy schemes can be a preferable option in patients with a low chance of complete R0 recession, especially in surgical.

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