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18+0-23+6. gebelik haftalarında fetal nazal kemik uzunluğunun değerlendirilmesi
2019
Journal:  
Ortadoğu Tıp Dergisi
Author:  
Abstract:

Amaç: Etnik farklılıklar gösteren ve kromozomal anomalilerle ilişkisi bildirilen fetal nazal kemik uzunluğunun 18+0-23+6. gebelik haftaları arasındaki nomogramlarının oluşturulmasıdır. Materyal ve Metod: Ocak 2009-Eylül 2014 tarihleri arasında, 18+0-23+6 gebelik haftalarında, US bulguları normal olan ve doğum sonrası anomali saptanmayan 2653 fetus retrospektif olarak değerlendirildi. Detaylı fetal anomali taraması yapılan her fetusun biparietal çapı (BPD), kafa çevresi (HC), karın çevresi (AC), femur uzunluğu (FL), nazal kemik (NK) uzunluğu ve ortalama gebelik haftası (GH) kaydedildi. NK uzunlukları ile GH, BPD, HC, AC ve FL arasında korelasyon analizi yapıldı. Her gebelik haftası için 5-10-25-50-75-90-95. persentil değerleri hesaplandı. Bulgular: Çalışmaya dahil edilen 2626 gebenin 27’sinda ikiz gebelik saptandı. Gebelerin yaşları 17-46 yıl (30,02 ± 5,78 yıl) arasındaydı. Çalışmamızda, 18 ile 23. gebelik hafta arasında sırasıyla 159, 214, 528, 599, 563, 583 fetus mevcuttu ve fetal NK uzunluğu ortalama değerleri sırasıyla 5,5 ±0,85; 6,3±0,83; 6,6±0,81; 6,9±1; 7,1±0,86; 7,6±0,89 (minimum 4 mm ve maksimum 10,1 mm) olarak bulundu. NK uzunlukları GH, BPD, HC, AC ve FL artışı ile lineer olarak arttı. Korelasyon analizinde fetal NK uzunluğu GH, BPD, HC, AC ve FL ile anlamlı pozitif korele bulundu (p<0,001). Sonuç: Çalışmamızda bölgemize ait 18+0-23+6. gebelik haftalarında sağlıklı fetuslarda nazal kemik uzunluğu nomogramları oluşturduk. Bu referans değerlerin, prenatal taramada nazal kemik hipoplazisi tanısında kullanılabileceğini düşünmekteyiz.

Keywords:

18+0 to 23+6. Evaluation of fetal nasal bone length during pregnancy weeks
2019
Author:  
Abstract:

Purpose: To establish the nomograms of fetal nasal bone length the ethnic differences and relationship between chromosomal abnormalities, between 18 +0-23 +6 gestational weeks. Material and Method: In this study, 2653 fetus between 18 +0-23 +6 gestational weeks had normal US findings and had not postnatal anomaly were retrospectively evaluated between January 2009 and September 2014. After detailed fetal anomaly scan, biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), nasal bone (NB) length and average gestational weeks (GW) of each fetus were recorded. Regression analyses were performed between NB length and GW, BPD, HC, AC and FL. The reference values for 5-10-25-50-75-90-95. percentiles were established for each gestational week. Results: In this study, 27 twin pregnancies were detected in the 2626 pregnant women (age range, 17-46 years; average age, 30.02 ±5.78 years). There were 159, 214, 528, 599, 563, 583 fetuses and the average NB lengths were 5.5 ± 0.85, 6.3 ± 0.83, 6.6 ± 0.81, 6.9 ± 1, 7.1 ± 0.86, 7.6 ± 0.89 (minimum 4 mm and maximum 10.1 mm) between 18 +0-23 +6 gestational weeks, respectively. NB length was increased linearly consistent with GH, BPD, HC, AC and FL during 18 +0-23 +6 gestational weeks. In correlation analysis, the fetal NB length were significantly correlated with GW, BPD, HC, AC and FL (p<0.001). Conclusion: In our study, we established the NB length nomogram in healthy fetuses between 18 +0-23 +6 gestational weeks. We think that this reference values can be used for diagnosis of nasal bone hypoplasia in prenatal screening.

Keywords:

Evaluation Of Fetal Nasal Bone Length During 18+0-23+6 Gestational Weeks
2019
Author:  
Abstract:

Purpose: To establish the nomograms of fetal nasal bone length reported the ethnic differences and relationship between chromosomal abnormalities, between 18+0-23+6 gestational weeks. Material and Method: In this study, 2653 fetus between 18+0-23+6 gestational weeks had normal US findings and had not postnatal anomaly were retrospectively evaluated between January 2009 and September 2014. After detailed fetal anomaly scan, biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), nasal bone (NB) length and mean gestational weeks (GW) of each fetus were recorded. Regression analyses were performed between NB length and GW, BPD, HC, AC and FL. The reference values for 5-10-25-50-75-90-95. percentiles were established for each gestational week. Results: In this study, 27 twin pregnancies were detected in the 2626 pregnant women (age range, 17–46 years; mean age, 30.02 ±5.78 years). There were 159, 214, 528, 599, 563, 583 fetuses and the mean NB lengths were 5.5 ± 0.85, 6.3 ± 0.83, 6.6 ± 0.81, 6.9 ± 1, 7.1 ± 0.86, 7.6 ± 0.89 (minimum 4 mm and maximum 10.1 mm) between 18+0-23+6 gestational weeks, respectively. NB length was increased linearly consistent with GH, BPD, HC, AC and FL during 18+0-23+6 gestational weeks. In correlation analysis, the fetal NB length were significantly correlated with GW, BPD, HC, AC and FL (p<0.001). Conclusion: In our study, we established the NB length nomogram in healthy fetuses between 18+0-23+6 gestational weeks. We think that this reference values can be used for diagnosis of nasal bone hypoplasia in prenatal screening.

Keywords:

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Ortadoğu Tıp Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

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Ortadoğu Tıp Dergisi