Özet:

Goal: Chronic kidney disease (CBH) is a major health problem that increases its prevalence and affects many systems. One of the problems caused by KBH is bone mineral diseases. For many reasons, osteoporosis is increasing in these patients. The aim of this study is to evaluate the frequency of osteoporosis and the risk factors that affect it in patients who apply hemodialysis and peritoneal dialysis. Tools and Methods: Patients over the age of 18 who took the Dual Energy X-Ray Absorbciometry (DEXA), which was considered dangerous in terms of bone mineral disease followed by the Periton Dialysis Clinic and Hemodialysis Clinic. The total number of patients involved is 74. 37 patients were taken from the peritonal dialytic clinic, 37 patients from the hemodial clinic. The criterion for removal from the study is that there is a bone mineral disease associated with any cause other than KBH. The following parameters we think will affect the development of osteoporosis in these patients have been studied: age, menopause age, dialytic time, smoking, use of calcium-containing or non-containing phosphate binding, broken history, kt/v ratio indicating hemodial activity, bikarbonate, hemoglobin, creatine, calcium, phosphorus, parathormone (PTH), triglyceride, low-dancite lipoprotein (LDL) cholesterol, high-dancite protein (HDL) cholesterol, albumin, 25 OH vitamin D levels and DEXA femur vertebra L1-L4 T scores are charged in the SPSS23 program. The statistical analysis of these data has been performed. Results: 32 (43%) of the 74 patients involved in our study were diagnosed with osteoporosis. Of the 32 patients with osteoporosis, 17 are women and 15 are men. In patients with osteoporosis, body weight (p:0,001), calcium levels (p:0,01), 25 OH vitamin D levels (p:0,039), non-calcium phosphate binding use (p:0,042) were determined in relation to osteoporosis. In the regression analysis with these factors, the type of dialytic is also involved, the most important factor is the body weight. The lower the body weight, the higher the risk of osteoporosis is detected. In the study we conducted, 35% less osteoporosis was detected in patients using peritoneal dialyse (p: 0.159). The result: in those with recent renal disease (SDBH), osteoporosis is a major cause of mortality and morbidity. For many reasons, these patients cannot be treated properly for osteoporosis and the development of osteoporosis cannot be prevented. Therefore, new studies are needed to determine the appropriate method of renal replacement treatment in patients who are at risk in this regard.