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 Görüntüleme 13
 İndirme 2
Parathyroidectomy Results in Primary Hyperparathyroidism: Analysis of the Results From a Single Center
2021
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Şişli Etfal Hastanesi Tıp Bülteni
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Özet:

Objectives: The curative treatment of primary hyperparathyroidism (PHPT) is surgery. Persistent and recurrent disease may develop after surgical treatment. In this study, we aimed to evaluate the surgical cure rate in patients who underwent surgery for PHPT in our clinic. Methods: The data of patients who underwent parathyroidectomy for PHPT by two experienced surgeons between 2000 and 2015 in our clinic were retrospectively evaluated. Patients who were followed for at least 6 months after their first parathyroidectomy were included in the study. Surgical cure and persistent and recurrent disease rates were evaluated in patients. Results: During this period, 368 interventions were performed in 357 patients (293 F and 64 M) who were operated for PHPT in our clinic, with a mean age of 54.9±13.1 years. In the first surgery, 116 patients (32.5%) had bilateral neck exploration, 251 patients (67.5%) had unilateral neck exploration (UNE) or focused parathyroid surgery (FPS). In the first operation, 343 patients (96.1%) had cure, 14 patients (13 F and 1 M) remained persistent. Secondary surgical intervention was performed in 11 patients. UNE or FPS was performed to 10 patients (90.9%); partial sternotomy was performed to one patient. Ten of the patients had cure. Three of these patients had a solitary parathyroid adenoma that was not removed in the first surgery, and seven patients had a second adenoma. Four patients remained persistent (1.1%). Recurrent disease developed in four patients during follow-up (1.1%). Total cure rate was 97.8%. Conclusion: The only definitive treatment for PHPT is surgery. High surgical cure can be achieved by pre-operative evaluation and appropriate surgical planning. However, persistent PHPT may develop, especially due to double adenoma or ectopic location. Patients with persistent PHPT can be evaluated with repeat imaging methods and with appropriate surgical planning, a high cure rate can be obtained in secondary surgery, which can increase the total surgical cure rate. Recurrence rate is rare.

Anahtar Kelimeler:

Results of parathyroidectomy in primary hyperparathyroids: analysis of single-center results
2021
Yazar:  
Özet:

Curative treatment of primary hyperparathyroid (pHPT) is a surgeon. After surgery, persistence and disease can develop. In this study in our clinic we aimed at evaluating the rate of surgical cur in patients undergoing surgery with the cause of pHPT. In our clinic, the data of patients with parathyroidectomy due to pHPT were evaluated retrospectively by 2 surgeons with experience between 2000-2015 years. Patients followed for at least 6 months after the first parathyroidectomy were included in the study. In patients, the surgical cur, persistence and nursing rates were assessed. Results: In this period, 357 patients (293K, 64E) with an average age of 54,9+13,1 years, who were operated due to pHPT in our clinic, 368 initiatives were applied. In the first operation, 116 patients (32,5%) were subjected to bilateral neck exploration (BBE), 251 patients (67,5%) were subjected to unilateral neck exploration (UBE) or focused surgery (OC). In the first surgery, 343 patients (96.1 percent) were curated, 14 patients (13K, 1E) (3.9 percent) persisted. The preoperative assessment resulted in a secondary surgical procedure for 11 patients. 10 patients (90.%) were given UBE or OC, 1 patient was given partial sternotomy. 10 of the patients were taken. In 3 of these, solitary parathyroid adenoma was not removed during the first surgery, and in 7 patients there was a second adenoma. Four patients remained persistent (1.1%). In four patients, the disease developed in the follow-up (1.1%). The total currency rate was 97.8%. The only definitive treatment of pHPT is the surgeon. High surgical curve can be obtained by preoperative assessment and appropriate surgical planning. However, p-pHPT may develop especially depending on double adenoma or ectopic settlement. Patients with p-pHPT can be evaluated by revision methods, and with appropriate surgical planning, a high cur rate in secondary surgery can be achieved, which can increase the total surgical cur rate. The rate is rare. (SETB-2021-03-079)

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2021
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Dergi Türü :   Ulusal

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