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Amaç: Bu çalışmada talasemi majör ve intermedia hastalarında arteryel sertlik parametrelerinin ekokardiyografik ve osilometrik (arteriograf) yöntemlerle incelenmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmaya her iki cinsiyetten 44 gönüllü katılımcı (24 talasemi hastası, 20 kontrol grubu) alındı. Hastaların hematolojik ve hemodinamik parametreleri kayıt edildi. Arteryel sertlik göstergesi olarak aortik arttırma göstergesi (aortic AG), nabız dalga hızı (NDH), aortic strain, distensibilite ve aortic sertlik indeksi bakıldı. Nabız dalga hızı ve aortic AG arteriyograf ile diğer parametreler ekokardiyografik olarak ölçüldü. Bulgular: Vasküler kompliyans belirleyicisi olarak bakılan parametrelerden aortik strain ve arteryel sertlik indeksi iki grup arasında anlamlı saptanmıştır. Aort nabız dalga hızı talasemi hasta grubunda sınırda anlamlı saptandı. Doku doppler ölçümlerinden erken (E‟) ve geç (A‟) mitral anüler diyastolik doluş hızları beta talasemi hastalarında kontrol grubuna göre anlamlı düşük saptandı. Sonuç: Ekokardiyografik doku doppler değerlendirmesi talasemi hastalarında diyastolik disfonksiyon gelişimini belirlemede yararlı bulunmuştur. Arteryel sertlik indeksleri, özellikle aortic strain, arteryel sertlik indeksi ve nabız dalga hızı, talasemi hastalarında demir birikimine bağlı vasküler yaşlanmayı belirlemede başvurulabilecek kolay ve güvenilir ölçümlerdir.
Purpose: This study is aimed at evaluating women who have been born in terms of Obstructive Defection Syndrome and constipation and determining the effect of the form of birth on Obstructive Defection Syndrome. The research universe was composed of 239 women who have made a little birth, applying to the gynecological clinic of an educational research hospital. The data of the study was collected with the survey form, which contains the socio-demographic and obstetric characteristics of the participants prepared on the basis of literature, "Obstructive Expression Score" and "Bristol Gaita Scale". Results: 60% of the participants were vaginal, and 40.0% were caesarean. 46.4 percent of participants were diagnosed with constipation and 4.6 percent obstructive defection syndrome. There was no statistically meaningful relationship between obstructive defection syndrome and age, form of birth and menopause. The Bristol gaita score has found a statistically meaningful relationship between the form of birth. It has also been established that there is a meaningful relationship between women’s obstructive defection syndrome scores and Bristol gaita scores. The result is that obstructive defecation syndrome has been determined to have a low rate of living and a high rate of constipation. Due to the high rate of constipation living in pregnant women, it is recommended to support constipation preventive approaches (pregnancy mobilization, fiber food consumption), to be advised by the health team and to conduct randomized controlled studies on the subject.
Purpose: The aim of this study was to evaluate arterial stiffness with echocardiographic and oscillometric (TensioMed arteriography) methods in thalassemia patients. Materials and Methods: We enrolled 44 participants from both gender (24 thalasemia patients, 20 control patients). Hematologic and hemodynamic parameters were recorded. Arterial stiffness was assessed non-invasively by measurement of pulse wave velocity, augmentation index, aortic strain, distensibility and arterial stiffness index by using TensioMed arteriography and echocardiography. Results: Aortic strain and arterial stiffness index were found to be significant between two groups. Pulse wave velocity had borderline significance between thalasemia and control patients. Tissue doppler early (E ') and late (A') mitral annular diastolic filling velocities in patients with beta thalassemia were significantly lower than the control group. Conclusion: Tissue doppler echocardiographic evaluation was useful in determining the development of diastolic dysfunction in patients with thalassemia. Arterial stiffness indices, especially aortic strain, arterial stiffness index and pulse wave velocity are a useful and easy methods to predict risk of vascular aging at thalassemia patients.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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