Abstract:

Purpose: Non-obesity is to evaluate hematological parameters in premature adrenal occurrences and to show the correlations of these parameters with androgen. Tool and Method: This study is a case control study and the patient’s files were investigated retrospectively. PA was diagnosed with prepubertal between the ages of 6-9 and 44 children with 45 children similar to age and gender without any systemic disease were included in the study. Intergroup hemogram parameters were compared, correlations with androgen levels were assessed. Results: The average age in the case group was 7.61±1 years, while in the control group it was 7.42±0.9 (p>0.05). Compared to the case and control group, erythrosite numbers (5,07±0,22, 4,87±0,31; p<0,05), hemoglobin levels (HGB) (13,77±0,79, 12,89±0,84; p<0,05), average erythrosite volume (81,83±3,73, 79,99±3,74; p<0,05) and erythrosite distribution range (12,71±1,80, 13,56±0,66; p<0,05) were different. There was also a positive correlation between the dehydroepiandrosterone-sulfate level and the Hgb level (r=0.27; p=0.03). The result: Higher levels of Hgb and erythrosite in premature adrenal occurrences may be associated with early accelerated functional activity in androgen biosynthesis stages observed in these occurrences. There is a need for greater work on this issue.

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