Abstract:

Objective: Urinary stone disease is a growing entity in both children and adults. It is an important cause of morbidity in endemic countries such as Turkey. The aim of this study was to identify clinical features and metabolic disturbance of pediatric urinary stone disease in Konya province.Material and Methods: Retrospective analysis of patients with diagnosis of urinary stone disease was conducted. Those with complete demographics, imaging and laboratory results were included. Ultrasonography and computed tomography without contrast was used to obtain stone location and size. Metabolic analysis were based on spot urinary excretions in children without potty training where 24-hour urine samples were used to identify urinary oxalate, citrate, cystine, calcium, uric acid and creatinine levels.Results: A total of 107 males and 100 females were included in the study. Male/female ratio was 1.1 whereas median age was 1.6 years range 2 months - 16.1 years . Most common complaint of admission was urinary tract infection 25.1% followed by abdominal/side pain 18.4% , discomfort 17.4% and microscopic/macroscopic hematuria 15.5% . Metabolic disturbances were found in 150 patients. Most common metabolic abnormalities were hypocitraturia 51 patients, 24.6% and hypercalciuria 40 patients, 19.3% , respectively.Conclusion: Results of our study indicate most common metabolic abnormality in children with urinary stone disease in Konya province is hypocitraturia. Necessary test in order to evaluate metabolic disturbance should be obtained in every pediatric urolithiasis patient, thus the risk of renal morbidity should be decreased

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