Abstract:

The interactions between foods and drugs are clinically important subjects. When some foods are taken with some drugs simultaneously, it is observed that there are some changes in the bioavailability, pharmacokinetic, pharmacodynamic, and therapeutic effects of the drugs. In addition, the therapeutic effects of many drugs change depending on individuals’ nutrition status. Some drugs affect the bioavailability and metabolism of the nutrients or taste sensation and appetite status. As a result of this, there may be certain clinical problems which have important outcomes such as the deficiencies of some vitamins and minerals, the changes of fluid-electrolyte balance and body weight. Although many of the mechanisms about food and drug interactions have been clarified, future research is expected to deal with the unclarified points.

Keywords: