Abstract:

Cancer is still the major cause of mortality and morbidity around the world. Even with the advancements in medical science the number of patients recovering from the disease is low and furthermore chances of tumor relapse and metastasis complicate the disease further. Present tumor therapies either fail to specifically target cancer cells or are prohibitively costly. Significantly, even after decades of research we still do not clear understand the events which initiate tumor formation and thereafter their unchecked growth into a gigantic tumor mass. Like the formation of the universe following the big bang remains a mystery, the formation of the tumor mass following the generation of a single cancer cell is also elusive. Gravitational force plays a major role in shaping our universe, our lives and even cellular biological processes. Similarly, cancer cells could communicate and sense each other through mechanical forces, which have evolved to work in an environment where there’s gravity. This thought has motivated various research works to observe the effect of gravity on cancer cells. This review highlights the effect of gravity on the cancer cells.

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