Özet:

Objective: To compare the histopathological features of symptomatic endometrial polyps excised in the premenopausal period in women with different body mass index and to investigate whether the presence of obesity may be a risk factor for premalignant / malignant degeneration of polyps. Methods: The histopathological findings of premenopausal women who applied for abnormal uterine bleeding and underwent operative hysteroscopy for endometrial polyps were retrospectively analyzed. Findings were recorded as benign (polyp), premalignant (hyperplastic polyp ± nuclear atypia), malignant (carcinoma developed on the basis of polyp). Results: While premalignant lesions were detected in 23 (3.7%) of six hundred and eighteen women, malignancy was not observed in any of the cases. The frequency of obesity in the group with premalignant findings was significantly higher than the group with benign findings. As a result of the regression analysis, the presence of obesity increased the probability of premalignant endometrial polyp approximately 4.5 times compared to normal weight individuals. Conclusion: Endometrial polyps detected in the etiology of abnormal uterine bleeding in the premenopausal period are unlikely to be premalignant / malignant. However, the realization of this possibility increases significantly in the presence of obesity.