Abstract:

Mushrooms are known to be nutritive and medicinal food stuff, which are good sources of some vitamins and essential minerals. They also contain some therapeutic agents, thus they have been used against several health problems for hundreds of years. The aim of this study is to determine the in vitro antimicrobial activity of Desarmillaria tabescens (Scop.) R.A. Koch & Aime 2017. D. tabescens samples were air dried and extracted by using ethanol. Antimicrobial activity of D. tabescens ethanol extracts were investigated against several Gram positive and Gram negative bacteria strains, fungal strains, which are either standard or isolated from food and some multi drug resistant (MDR) clinical isolate bacteria namely, Bacillus subtilis DSMZ 1971, Candida albicans DSMZ 1386, Enterobacter aerogenes ATCC 13048, Enterococcus durans, Enterococcus faecalis ATCC 29212, Enterococcus faecium, Escherichia coli ATCC 25922, Klebsiella pneumoniae, Listeria innocua, Listeria monocytogenes ATCC 7644, Pseudomonas aeruginosa DSMZ 5071, Pseudomonas fluorescence P1, Salmonella enteritidis ATCC 13075, Salmonella infantis, Salmonella kentucky, Salmonella typhimurium SL 1344, Staphylococcus aureus ATCC 25923, Staphylococcus epidermidis DSMZ 20044, Staphylococcus aureus (MDR), Escherichia coli (MDR), Klebsiella pneumoniae (MDR), Acinetobacter baumannii (MDR) and Streptococcus pneumoniae (MDR) by using the disk diffusion method. As a result, it was observed that ethanol extracts of D. tabescens has low to medium antimicrobial activity against several Gram positive and Gram negative microorganisms tested. The antimicrobial activity of D. tabescens especially observed against K. pneumoniae (MDR) and S. pneumoniae (MDR) is found to be remarkable.