Özet:

Objective Since many studies focused on the relationship between mean platelet volume (MPV) and severity of type 2 diabetes mellitus (T2DM) or investigated MPV and coronary artery disease (CAD) mostly on acute coronary syndrome (ACS), this study primarily focused to investigate if MPV values have any relation with different levels of CAD specifically in T2DM patients, who had no previous coronary artery disease, and no ACS history. Materials And Methods T2DM patients who had first coronary angiography (CAG) between November 2019 and February 2020, and whose after night fasting blood tests were performed before CAG were included. Two cardiologists, blinded to the patients, evaluated angiographies. Patients have divided into groups accordingly; normal coronary artery (Group 1), non-critic stenosis (Group II), and severe CAD (Group III) according to the Gensini score. Patients’ demographics, heart rate, risk factors of CAD, and blood test including MPV were also collected. Results A total of 180 patients (88 female, 92 male) were involved in the study. There was no significant relation between MPV and the severity of CAD in T2DM patients (p=0.228). The mean age of the Group I group was significantly lower than in other groups (p=0.228), and there were significantly lower males in Group I than other groups (p=0.0001). The triglycerides levels were significantly low in Group I than in other groups (p=0.021 and p=0.006). Conclusion MPV values were not associated with the severity of CAD in stable patients. Older age, male gender, higher levels of triglycerides, and initial glucose levels were significantly related to the severity of CAD in T2DM patients.

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