Abstract:

Purpose: This study was aimed at investigating the quality of sleep in patients with ankylosan spondylitis (AS) and revealing the clinical parameters that predict the quality of sleep and depression in AS. Method and method: This study included 100 healthy individuals, aged/gender-compatible with the patient and patient group of 100 AS. AS activity was assessed by Bath AS Disease Activity Index (BASHAI), AS Disease Activity Score (ASDAS-ESH, ASDAS-CRP) and Visual Analog Scale (GAS). The functional status was assessed by the Bath AS functional index (BASFI). Ankylosan Spondylitis Quality Survey (ASYKA) was used to evaluate the quality of life associated with the disease. The Pittsburgh Sleep Quality Index (PUKI) and the Beck Depression Reserve (BDE) for psychological assessment were applied to all participants for sleep assessment. In patients with AS, sleep problems and depressive symptoms increased significantly compared to healthy individuals. In patients with AS with poor sleep quality, all AS clinical parameters were significantly more load-sized than in patients with AS with good sleep quality. Correlation analysis found that poor quality of sleep, depressive symptoms and low quality of life were strongly linked to each other and to AS clinical parameters. The most effective for sleep problems was the high BASDAI scores and followed by the high BASFI, GAS, ASDAS-ESH scores and young age. High BASFY and GAS scores were the indicators of depressive symptoms. The findings show that bad sleep, depressive symptoms and low quality of life may have a negative impact on the AS clinic and therefore the quality of sleep and depression should not be neglected in the examinations of patients with AS.

Keywords: