Özet:

OBJECTIVES To evaluate the prognostic factors and the treatment results in early stage glottic laryngeal carcinoma patients treated with radiation therapy. METHODS The records of 83 patients (80 males; 3 females; mean age 62 years; range 40 to 85 years) treated with radical radiotherapy at Ege University Medical School Department of Radiation Oncology during January 1995-December 2004 were studied retrospectively. RESULTS Twenty-nine patients had (34.9%) T1a, 29 patients had (34.9%) T1b and 25 patients had (30.1%) T2 stage disease. During a median follow-up of 56 months, 13 patients had failures. Five year local control rates were 90.5% in T1 and 73.2% in T2 patients. Locoregional control rates were 89% in T1 and 70.5% in T2 patients. Treatment interruption more than 5 days was noted as a prognostic factor affecting local and locoregional control. Five year disease specific survival rates were 94% in T1 and 79% in T2 patients, T stage and radiotherapy interruption more than 5 days were noted as prognostic factors affecting disease specific survival. CONCLUSION Curative radiotherapy is an effective treatment modality in early stage glottic laryngeal cancer.

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