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  Citation Number 4
 Views 10
 Downloands 4
Physiological Effects of Commonly Used Medicinal and Aromatic Plant's Antioxidant Phytochemicals
2015
Journal:  
Kocatepe Veteriner Dergisi
Author:  
Abstract:

Son yıllarda, serbest radikal kimyası, antioksidanlar, eksojen fitokimyasal antioksidanlar ve bunların güvenli kullanımına ilgi büyük olmuştur. Oksidatif strese yol açan serbest radikaller, reaktif oksijen ve nitrojen türleri, çeşitli endojen sistemlerde vücudumuz tarafından üretilir. Bunun dışında farklı fiziksel ve kimyasal koşullara veya patolojik durumlara maruziyet de oksidatif stres kaynağı olabilmektedir. Normal koşullarda serbest radikaller ve antioksidanlar arasında bir denge ve bir uyum vardır. Bu canlı için gereklidir. Serbest radikalleri makul sınırlarda tutan vücudun antioksidan savunma yeteneğinin aşılması halinde oksidatif stres ile karşılaşılır. Böylece, lipidler, proteinler ve DNA'da hasar oluşturarak hastalıklara yol açan bir dizi reaksiyon tetiklenir. Bu nedenle antioksidan dış kaynakların kullanımı oksidatif stresi önelmede veya onunla başa çıkmada sıkça karşımıza çıkmaktadır. Ancak bütillenmiş hidroksitoluen (BHT) ve butillenmiş hidroksianisol (BHA) örneklerinde olduğu gibi, kimi sentetik antioksidanların sağlık için tehlikeli olduğunun anlaşılması, araştırmacıları antioksidan aktiviteye sahip etkili, toksik olmayan, doğal, bitkisel bileşiklerin aranmasına yoğunlaştımıştır. Bu kapsamda, derlemede oksidatif stres aracılı hücresel hasar ve hastalıklara karşı fonksiyonel kabul edilen antioksidan fiyokimyasalların temel özellikleri ve rolleri üzerinde özet bir bakış sağlamak amaçlanmıştır.

Keywords:

Physiological Effects of Commonly Used Medicinal and Aromatic Plant's Antioxidant Phytochemicals
2015
Author:  
Abstract:

In recent years, the interest in free-radical chemistry, antioxidants, exogenous phytochemical antioxidants and their safe use has been great. Free radicals, reactive oxygen and nitrogen types that lead to oxidative stress are produced by our body in various endogenous systems. Exposure to different physical and chemical conditions or pathological conditions can also be an oxidative source of stress. In normal conditions, there is a balance and a harmony between free radicals and antioxidants. This is necessary for living. When the body’s antioxidant defense capacity, which keeps the free radicals within reasonable limits, is overcome, it is faced with oxidative stress. Thus, a series of reactions that lead to diseases are triggered by causing damage to lipids, proteins and DNA. Therefore, the use of external sources of antioxidants often comes to us in preventing or dealing with oxidative stress. But, as in the samples of botilized hydroxitoluene (BHT) and botilized hydroxyanisol (BHA), the understanding that some synthetic antioxidants are dangerous for health, researchers have focused on the search for effective, non-toxic, natural, plant compounds with antioxidant activity. In this context, the collection aims to provide a comprehensive overview of the basic characteristics and roles of antioxidant phytochemicals which are considered to be functional against cell damage and diseases through oxidative stress.

Keywords:

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2014








Kocatepe Veteriner Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

Metrics
Article : 698
Cite : 2.316
2023 Impact : 0.084
Kocatepe Veteriner Dergisi