Özet:

Objective: To investigate the effects of bispectral index-controlled use of magnesium on propofol consumption, periprocedural hemodynamic response and patient comfort. Materials and Methods: A total of 60 patients were enrolled in the study. In Group I (magnesium), a single dose 50 mg/kg magnesium sulfate (diluted with 100 mL 0.9% NaCl) was administered 10 minutes before the beginning of the procedure. Initial dose of 0.5 mg / kg propofol bolus was applied. The maintenance dose of propofol was 60 mcg / kg /min. During the procedure, the propofol infusion was increased by titration until the bispectral index (BIS) value of 70 was achieved. In Group II (saline), 100 ml 0.9% NaCl was administered 10 minutes before the beginning of the procedure. The propofol bolus and maintenance doses, and target BIS values were the same as those in Group I. Results: When BIS values were compared between the groups, the initial BIS values in the magnesium group (Group 1) were significantly higher than those of the saline group (Group 2) (p<0.05). The time to reach BIS 70 was significantly lower in the magnesium group (p<0.05). Propofol consumption was greater in Group 2 than in Group 1 (p <0.05). The time to reach BIS 70 was significantly lower in Group 1 (p <0.05). No significant difference was found between the groups in terms of patient and endoscopist satisfaction (p ˃ 0.05). Conclusion: The use of magnesium in addition to propofol may be an efficient and reliable option to reduce the drug consumption during colonoscopic interventions.

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