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  Citation Number 2
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MEME KANSERİNDE GENETİK RİSK FAKTÖRLERİ: BRCA1 VE BRCA2 GENLERİ
2021
Journal:  
ERÜ Sağlık Bilimleri Fakültesi Dergisi
Author:  
Abstract:

Meme kanserinde erken tanı tedavinin başarını oranını artırmaktadır. Erken tanı için bireyin meme kanser risk faktörleri, belirti, bulguları ve tarama yöntemleri hakkında bilgi sahibi olması gerekmektedir. Özellikle ailesinde meme kanser öyküsü bulunan bireylerin genetik risk faktörü açısından tarama yaptırması önerilmektedir. Breast Cancer-1 ve Breast Cancer-2 genleri tümör baskılayıcı ve hücrelerin anormal büyümelerini önleyici birer gendir. Tümör oluşumu bu gen proteinlerinin herhangi birinin inaktivasyonu ya da mutasyonu sonucunda oluşmaktadır. Literatür bilgilerinden yola çıkılarak hazırlanan bu derlemede meme kanseri tanısı almada genetik risk faktörü taşıyan bireylerde özellikle Breast Cancer-1 ve Breast Cancer-2 protein genlerinin araştırılmasının önemi konusunda farkındalık sağlanması amaçlanmıştır.

Keywords:

Genetic risk factors in breast cancer: BRCA1 and BRCA2 genes
2021
Author:  
Abstract:

It increases the success rate of early diagnosis of breast cancer. For early diagnosis, the individual must be aware of breast cancer risk factors, symptoms, findings and screening methods. It is recommended that individuals with a history of breast cancer in their family make a screening in terms of the genetic risk factor. Breast Cancer-1 and Breast Cancer-2 genes are a tumor suppressant and prevent the abnormal growth of cells. The formation of the tumor occurs as a result of the inactivation or mutation of any of these genetic proteins. This collection, based on literary information, aims to provide awareness of the importance of the study of Breast Cancer-1 and Breast Cancer-2 protein genes in individuals with genetic risk factor in breast cancer diagnosis.

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0
2021
Author:  
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ERÜ Sağlık Bilimleri Fakültesi Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 129
Cite : 825
2023 Impact : 0.034
ERÜ Sağlık Bilimleri Fakültesi Dergisi