Özet:

We aimed to compare the two drugs, sugammadex and neostigmine,with regard to reversing neuromuscular blockage provided by rocuronium under desfl urane anaesthesia.METHODS: In this prospective randomized trial, 80 patients with ASA I-III scores were included. The study included the patients having lower abdominal and urological surgery under generalanesthesia. In order to evaluate awakening and extubation differences, the participants were assigned into two study groups S and N. Group S and N included the participants who were givensugammadex and neostigmine, respectively to reverse the neuromuscular blockage created by rocuronium. In both groups extubation was performed when previously clarifi ed clinical criteria werefull and after TOF value reached 0.90. Other than TOF value at decurarization moment, minutely TOF values were also recorded for ten minutes after decurarization. The time period between decurarization and extubation was recorded as the extubation time.RESULTS: There was no statistical difference between the demographic data. The extubation time in Group S was significantly shorter. The TOF values of Group S at the 2nd, 3rd, 4th, 5th, 6th, 7th, 8th and 9th minutes were signifi cantly higher than that of Group N.CONCLUSION: In comparison with neostigmine, sugammadex results in faster decurarization and a shorter clinical extubation time following neuromuscular blockage induced by rocuronium administration under desflurane anaesthesia.

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