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Amaç: Elastografi doku elastisitesini değerlendiren yeni bir ultrasonografi tekniğidir. Bu çalışmanın amacı, glomerülonefritli hastalarda böbrek parankimini elastografi ile değerlendirmek ve hastaların laboratuvar verileri ile gerinim indeksi arasında ilişkiyi tespit etmektir. Gereç ve Yöntem: Bu çalışmaya glomerülonefritli 26 hasta (13 erkek, 13 kadın, ortalama yaş 41,67 ± 13,4) ile cinsiyet ve yaş eşleştirilmiş 20 sağlıklı kontrol grubu dahil edildi. Glomerülonefritli hastaların tahmini glomerül filtrasyon hızı (eGFR), serum kreatinin, spot idrar proteini, spot idrar kreatinin, spot idrar protein / kreatinin oranı kaydedildi. Tüm katılımcıların elastografi ile böbrek parankim incelemeleri yapıldı ve gerinim indeksleri ölçüldü. Bulgular: Glomerülonefritli hastalarda sağ ve sol böbrek gerinim indeksleri kontrollerden daha yüksekti (sağ 3,89 ± 0,82 ve 3,39 ± 0,78 p = 0,038, sol 3,94 ± 0,69 ve 3,24 ± 0,81 p = 0,003). Hastaların böbrek gerinim indeksleri ile tahmini glomerül filtrasyon hızı, serum kreatinin, spot idrar protein, spot idrar kreatinin, spot idrar protein/kreatinin değerleri ile anlamlı bir korelasyon saptanmadı (p˃ 0,05). Hasta ve kontrol gruplarının gerinim indekslerine dayanan ROC eğrisi analizindeki incelemede glomerülonefrit tanısı için gerinim oranı değerleri cut-off değeri 3,8, duyarlılık %61,5 ve özgüllük %85 idi. Sonuç: Elastogram indeksleri glomerülonefritli hastaları sağlıklı bireylerden ayırmak için kullanılabilir.
Purpose: Elastography is a new ultrasound technique evaluating the elasticity of the tissue. The objective of this study is to evaluate the renal parankimi in patients with glomerulonefritis with elastography and to identify the relationship between the patient’s laboratory data and the demand index. This study included 26 patients with glomerulonefritis (13 men, 13 women, average age; 41.67 ± 13.4) with gender and age matched 20 healthy control groups. The estimated rate of glomerulonefritis filtration rate (eGFR) in patients with glomerulonefritis, serum creatine, spot urine protein, spot urine creatine, spot urine protein / creatine was recorded. All participants were conducted renal parankim examinations with elastography and the demand index was measured. Results: In patients with glomerulonefritis, the right and left kidney demand index were higher than controlled (right; 3,89 ± 0,82 and 3,39 ± 0,78 p = 0,038, left; 3,94 ± 0,69 and 3,24 ± 0,81 p = 0,003). There was no significant correlation with the estimated glomerul filtration rate, serum creatine, spot urine protein, spot urine creatine, spot urine protein/creatine values (July 0,05). In the study of the ROC curve analysis based on the patient and control groups’ expectancy indicators, the expectancy ratio for the diagnosis of glomerulonefrite was cut-off values of 3.8, sensitivity of 61.5 % and specificity of 85 %. Result: Elastogram indicators can be used to distinguish patients with glomerulonefritis from healthy individuals.
Objective: Elastography is a new ultrasound-based technique able to assess tissue elasticity. The aims of this study were to evaluate the renal parenchyma with elastography in patients with glomerülonephritis and to determine the association between strain index and patients’ laboratory parameters. Material and Method: Twenty-three patients (13 men, 13 women; mean age 41.67 ± 13.4 years) with glomerülonephritis and 20 sex and age-matched healthy controls were enrolled in this study. Estimated glomerüler filtration rate (eGFR), serum creatinine, spot urine protein, spot urine creatinine, spot urine protein/creatinine ratio were recorded in patients with glomerülonephritis. Elastography examinations of renal paranchyma were performed for all participants and the strain ratio values were measured. Results: The right and left strain index values were significantly higher in patients with glomerülonephritis than in controls (right; 3.89±0.82 vs. 3.39±0.78 p=0.038, left; 3.94±0.69 vs. 3.24±0.81 p=0.003, respectively). The strain index scores did not showed any significant correlation with eGFR, serum creatinine, spot urine protein, spot urine creatinine, spot urine protein/creatinine ratio (for all, p˃ 0.05). On ROC curve analysis based on strain ratio values of the patient and control groups, the cut-off value for the diagnosis of glomerülonefritis was 3.8, with a sensitivity of 61.5% and a specificity of 85%. Conclusions: Strain index of elastography can be used to differentiate patients with glomerülonefritis from healthy individuals.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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