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Amaç: Kliniğimizde opere edilen sekonder akciğer neoplazmları incelenerek, primer tümör kontrol altında ikenyapılan metaztazektominin sağkalım üzerine olan etkilerinin araştırılması. Materyal metod: Bu çalışmada Ocak 2010 ile Ocak 2015 yılları arasında kliniğimizde sekonder pulmoner neoplazm nedeni ile opere edilen 29 olgu retrospektif olarak incelendi. Olgular yaş, cinsiyet, kardiopulmoner değerlendirmeler, primer tümörün histopatolojik tipi, sekonder tümörün evresi ve preoperatif radyolojik bulguları, hastalıksız yaşam süreleri, cerrahi insizyon şekilleri ve rezeksiyonun türü, komplet-inkomplet rezeksiyon sayıları, nodül sayıları, sağkalım süreleri açısından değerlendirildi. Bulgular: Olguların 9’u kadın (%31) 20’si (%69) erkek idi. En küçük yaş 18 en büyük yaş 75 (ortalama 56±12) idi. Olgularımıza toplam 38 cerrahi girişim uygulandı. En sık uygulanan cerrahi girişim 24 olguda (%63,2) posterolateral torakotomi (PLT), 14 olguda (%36,8) video yardımlı torakoskopik cerrahi (VATS) idi. Bir yıllık sağkalım %96, 3 yıllık sağkalım %72 ve 5 yıllık sağkalım % 58 olarak bulundu. Primer tümörün histopatolojik tipine göre en sık karsinom (%79,3) ikinci sıklıkta sarkom (%17,2) tespit edildi.Sarkomlarda pulmoner metastazektominin 5 yıllık sağkalım %40, karsinomlarda %73,5 olarak hesaplandı. Sonuç: Primer malignitesi kontrol altında ve ekstra pulmoner metastazı olmayan sekonder pulmoner neoplazmlı olgularda, metastazektomi, özellikle karsinomlarda sağkalıma önemli ölçüde katkı sağlanmaktadır. Çalışmamızda sekonder tümörün evresinin ve primer tümörün histopatolojik tipinin sağkalımı belirleyen esas faktörler olduğu görüldü.
Purpose: Studying the secondary lung neoplasms operated in our clinic, researching the effects of the metastazectomy under primary tumor control on survival. Material method: In this study, 29 facts operated in our clinic between January 2010 and January 2015 due to secondary lung neoplasm were examined retrospectively. Facts were assessed in terms of age, gender, cardiopulmonary assessments, the histopathological type of the primary tumor, the stage of the secondary tumor and preoperative radiological findings, the lifetime without disease, the forms of surgical insection and the type of resection, the total-incompleted resection numbers, the number of nodules, the survival periods. Results: 9 of the cases were women (31%) and 20 (69%) were men. The youngest age was 18 and the bigest age was 75 (medium 56±12). In total, 38 surgical procedures have been performed. The most commonly applied surgical initiative was in 24 cases (%63.2) posterolateral toracotomy (PLT), in 14 cases (%36.8) video-assisted toracoscopic surgery (VATS). One year survival was 96, 3 years survival was 72% and 5 years survival was 58%. The primary tumor's histopathological type was seen as a carcinoma (79.3%), the second-frequency sarcoma (17.2%), and the 5-year survival of pulmonary metastasectomy in sarcoma was calculated as 73.5% in the carcinoma. Result: Primary malignity is controlled and in secondary pulmonary neoplasm cases without extra pulmonary metastases, metastasectomy, especially in carcinomas, contributes significantly to survival. Our study found that the main factors determining the survival of the stage of the secondary tumor and the histopathological type of the primary tumor.
Objective: Secondary pulmonary neoplasms operated in our clinic were evaluated. The effect of pulmonary metastasectomy on survival was investigated. Material and Methods: In this study, between January 2010 and January 2015 in our clinic 29 cases operated for secondary pulmonary neoplasm were evaluated retrospectively. Cases were individually analysed according to their demographics. Our analysis criteria were age, gender, histopathological type of primary tumor, stage of secondary tumor and its preoperative radiological signs, length of life without illness, types of surgical incision and resection, numbers of complete-incomplete resections, number of pre/postoperative nodules, cardiopulmonary evaluations and length of survival. Results: 20 (69%) and 9 (31%) of our cases were male and female; respectively. Youngest case was 18 years old whereas oldest case was 75 years old. Mean age of cases was 56±12 years. Number of our cases was 29 and they had undergone 38 surgical intervention. Most common surgical intervention was posterolateral thoracotomy (PLT) in 24 cases. Secondary most common surgical intervention was Video Assisted Thoracoscopic Surgery (VATS) in 14 cases. In terms of histopathological type of primary tumor, most common types were carcinoma (79.3%) and sarcoma (17.2%). 5-year survival rate in pulmonary metastasectomy was 40% in sarcomas and 73.5% in carcinomas. It was observed that pulmonary metastasectomy was more beneficial in carcinomas than sarcomas. Conclision: In conclusion, metastasectomy significantly improves survival in secondary pulmonary neoplasm cases whose primary malignancy is under control without metastasis in any other extrapulmonary area. Stage of secondary tumor and histopathological type of primary tumor were observed as actual factors determining survival.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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