Özet:

Introduction: Over the last years, the incidence of multiple primary neoplasms has been increasing, with cases of primary prostate cancer and primary colorectal cancer being one of the most frequent. Case report: In the case of a 67-year-old patient with sigmoid cancer, a prostate cancer was found in pre-therapeutic imaging evaluations, later confirmed by histopathological examination. After colectomy with lymphadenectomy, he had received adjuvant chemotherapy, which was stopped because of persistent thrombocytopenia. A prostatectomy with lymphadenectomy was performed. After six months, Pet-PSMA showed bone lesions, so CyberKnife radiotherapy was performed on each. After another six month-free interval, the patient presented biochemical recurrence, so adjuvant “salvage” radiotherapy was performed with PSA value decreasing afterwards. Without hormonal therapy, which was declined for the moment by the patient, after six months, Pet-CT evidenced metastatic bone lesions and a secondary liver determination. Complete androgenic blockade type hormone treatment has been initiated, as well as chemotherapy, with imagistic complete response and stationary PSA value. Conclusions: In the cases of patients suffering from multiple cancers, serial and multimodal treatments are the only one able to ensure their healing, respectively their long-term survival

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