Özet:

INTRODUCTION: To investigate whether blood urea and/or creatinine levels which are also used as renal function tests could be a biochemical marker for uterine prolapse. METHODS: The resarch has been realized by retrospectively scrutinizing the patient files of 101 cases that have had undergone vaginal or abdominal hysterectomy. The preoperative blood urea and creatinine levels were noted. RESULTS: In the vaginal hysterectomy group; 30 (60 %), 17 (34 %), and 3 (6 %) cases out of 50 women had stage II, stage III and stage IV uterine prolapse, respectively whereas in the abdominal hysterectomy group, 3 (6 %) and 48 (94 %) cases out of 51 women had stage 0 and I uterine prolapse, respectively. There was no statistically significant difference between vaginal and abdominal hysterectomy groups in terms of preoperative blood urea levels (p=0.168, p>0.05), however there was a statistically significant difference between vaginal and abdominal hysterectomy groups in terms of preoperative blood creatinine levels (p=0.042, p<0.05). In the receiver operator ROC curve analysis for creatinine, the cut-off value which had the highest sensitivity and specifity and lowest false positive predictivity was found to be 1 mg/dl. DISCUSSION AND CONCLUSION: A postmenopausal woman who had a blood creatinine level higher than 1 mg/dl at random biochemical testing should be evaluated regarding uterine prolapse.

Anahtar Kelimeler: