Abstract:

Endometrium cancer is the most commonly seen gynecological malignited and the screening test for this cancer has not been determined. In this study, the relationship between the histopathology and the results of cervical swelling of patients with endometrial sampling due to postmenopausal bleeding was studied in our clinic. METHODS: 277 patients with endometrial sampling due to postmenopausal bleeding between 2008 and 2010 were examined in a retrospective manner as the pathological results and cervical smoothie performed within 6 months prior to biopsy. Diagnoses obtained from endometrial sampling were classified as serious endometrial pathology (endometrium cancer and atypical endometrial hyperplasia), benign endometrial pathology (atypical endometrial hyperplasia, endometrial polyps) and physiological endometrium (secretary, proliferative and atrophic endometrium). Diagnosis of cervical smell was classified as an abnormal and normal. The presence of benign endometrial cells (BEH), malign endometrial cells (MEH) and atypical glandular cells (AGH) was considered an abnormal smear. The average age of patients was 57.6 ± 8.3 years (41-86). In patients with severe endometrial pathology, the result of cervical swelling was observed by 23.3 percent BEH, 13.3 percent MEH, and 20 percent AGH. In patients with benign endometrial pathology, the BEH rate was 44.8%. This ratio was higher than other groups and was statistically meaningful (p1<0.05, p2<0.05, Ki-quare test). The sensitivity of cervical smearine in the detection of severe endometrial pathologies was 56.6%, the specificity 90.2, the positive predictive value 41.4, the negative predictive value 94.4%. DISCUSSION AND CONCLUSION: According to our findings, cervical smearine is low sensitivity in detection of severe endometrial pathologies and is not suitable for use in endometrium cancer screening. But in the postmenopathic period, smarded endometrial cells can be a early discovery of the presence of endometrial pathology. Evaluation of these patients with endometrial samples can provide early diagnosis and treatment.

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