Özet:

Introduction: Rhabdomyolysis is a clinical and biochemical syndrome, resulting from the exposure of the skeletal muscle to toxic substances or from diseases. The etiology of the rhabdomyolysis consists of the hereditary deficiency of muscle enzymes; drugs like colchicine, statins, and lithium; convulsion; trauma; viral infections; excessive exercise; and so on. Hypothyroidism is a clinical setting in which thyroid hormones are produced and secreted ineffectively.Case Report: In our article, two cases of rhabdomyolysis due to hypothyroidism are presented who got the diagnosis of hypothyroidism but had not gotten any treatment. It was seen that the clinical signs and symptoms of the patients recovered quickly with the beginning of hormone replacement, and muscle enzymes decreased back to normal levels.Conclusion: It should be remembered that depression of the respiratory system, cardiomegaly, pericardial tamponade, angina pectoris, congestive heart failure, and rhabdomyolysis can develop in those patients who are diagnosed with hypothyroidism and yet not treated properly

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