Özet:

Purpose: to investigate the effect of the FSH/LH rate on the results of controlled ovulation induction cycles performed with gonadotropin. Tools and Methods: The study included 66 patients with infertility diagnosis that was not explained in our clinic and ovarian hyperstimulation controlled by gonadotropin, continued with intrauterine insemination (IUI). The patient’s age, BMI, infertility time, total dose of gonadotropin used for induction, HCG day levels of estradiol (E2), HCG day endometrium thickness, basal FSH, LH, E2 levels, induction time, pregnancy formation and the number of developing follicles were recorded. Patients were divided into two groups in which the FSH/LH ratio is below 2 (group 1, n=42) and those 2 and above (group 2, n=24). The groups were compared statistically in terms of the indicated variables.  Results: The average age of 66 patients involved in the study was 26.71±1.01. There were no statistically significant differences in terms of age, BMI, FSH levels, and HCG day endometrium thickness pregnancy numbers (p>0.05). The level of estradiol considered on HCG day, the level of LH, the number of follicles, the FSH/LH ratio was significantly high in the group; the total dose of gonadotropin, the basal level of estradiol, and the induction time were statistically significantly low (p<0.05). There was a positive correlation between FSH/LH and HCG day estradiol levels, total gonadotropin doses, estradiol levels, induction time and follicle number. Result: According to the results of our study, increased basal FSH/LH rates are associated with poor over response in patients with ovulation induced due to unexplicable infertility.

Anahtar Kelimeler: