Özet:

Aim: To describe presenting features and clinical characteristics of ITP and evaluate clinical course, treatment modalities, and complications and determine the effects of preceding infection history, age, gender, treatment modality, and admission platelet count on relapse and chronicity in pediatric patients treated over a 4 year period. Material and Method: Forty cases with an age range of 4 months to 11 years mean 64.2±39.9 months who were diagnosed with ITP between January 2005 and June 2009 were retrospectively evaluated from medical records. Results: Eight patients 20 % progressed to chronic ITP. No difference was found between acute and chronic ITP groups with respect to gender, age, preceding viral infection and platelet count. Relapse developed in 12 patients 30 % , after a mean of 22±25.8 days. While 66.7 % 8 patients of the relapsed cases developed chronic ITP, 33.3 % 4 patients were evaluated as acute ITP: None of the cases who have not relapsed progressed to chronic ITP. Relapse rate was statistically significantly higher in the chronic group. Median platelet count at day 15 after diagnosis was significantly lower in the relapse group. It was found that treatment modality had no effect on relapse. Conclusions: Although platelet count at day 15 after diagnosis can be used in determining the patients who will relapse, since the number of cases are limited it is concluded that it would be better to evaluate this result in a prospective study including a larger study population

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