Özet:

Purpose: The non-thyroid disease syndrome can be triggered by the attack of chronic obstructive lungs disease (KOAH). The presence of thyroid function disorders and thyroid antibodies and other clinical and arterial blood gases, urethra, creatine, international normalized ratio (INR) etc. We aim to evaluate their relationships with parameters. Methods: In the 1-3. days of the KOAH attack, 21 facts (17 men / 4 women) were taken to study with non-invasive mechanical ventilation. Free T3, fT4, TSH levels, glucose, urethra, creatine, hematocrit, hemoglobin, prothrombin time (PT), active partial tromboplastin time (APTT) parameters, thyroid antibodies of the 10 events were evaluated. A control group of 17 healthy, non-smoking people who apply to the domestic clinic for the purpose of health check was created and similar parameters were evaluated. The analysis was carried out in the SPSS 17.0 statistical program. The findings: the average age of COPD is 5.95±10.63, the body mass index is 23.19±5.8 kg/m2 (n=21), the average age of healthy events is 54.35±7.33 kg/m2, the body mass index is 26.94±5.3 (n=17). The average fT3 was lower than the healthy control group in cases with KOAH, while the fT4 was higher (the patient group was mid±SD (median); fT3 2,52±0,48 (2,69), fT4 0,99±0,16 (1,01), TSH 0,95±0,7 (0,80). Free T3 was lower by 33.33% of the cases in the KOAH attack, while TSH was below normal values in 14.28% of the cases (respectively, p=0,001, p=0,001, p=0,009). Protrombin time was negatively correlated with fT3 (rs= -0,520, p=0,03). The negative correlation between Protrombin time and free T3 levels is a new finding found in this study. According to healthy facts, lower levels of fT3 found in the KOAH attack are also supported by other studies. (JAREM 2014; 1: 18-24)

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