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INTRODUCTION: To evaluate the effectiveness of combined trabeculotomy-trabeculectomy with mitomycin C for primary congenital glaucoma METHODS: The medical records of 7 patients' 13 eyes with primary congenital glaucoma who had combined trabeculotomy-trabeculectomy with mitomycin C were reviewed.SPSS 15.0 software for Windows was used for statistical analysis.®Preoperative and postoperative intraocular pressures were compared with Wilcoxon signed rank test.Results: Thirteen eyes of 7 (4 male, 3 female; average age 30.6 ± 22.4 months) patients who were operated between June 2006-May 2012 were included in the study.The average time of first presantation was 2.6 ± 1.1 (1-4) months, whereas the average time of first surgery was 5.3 ± 4.0 (1-12) months.Six patients had bilateral disease. Mean follow-up time was 25.9 ± 22.6 (1-54) months. Mean corneal horizontal diameter was 13.4 ± 0.9 (12-15) mm. Corneal edema was found in 53% of the patients. The surgical success rate (intraocular pressure < 21 mm Hg) of eyes with combined surgery alone was 53.8%, however this ratio was increased to 76.9% when additional surgeries were performed. DISCUSION AND CONCLUSION: Even though combined trabeculotomy- trabeculectomy with mitomycin C is an effective surgical option for primary congenital glaucoma, the surgical success rate is increased with additional surgeries

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