Özet:

This study aims to determine the levels of hematological and heart enzymes [cardial troponin-I (cTn-I), creatine kinase (CK), creatine kinase - myocardial band (CK-MB), lactate dehydrogenase (LDH) and aspartate aminoteansferase (AST)] and serum vitamins A, C and E and malondialdehit (MDA) in cattle with a sheep disease. The study material was made up of a total of 40 heads, including 20 heads (the vaccine group) and 20 heads (the vaccine group) that were diagnosed with sheep disease after general clinical trials. All animals (body temperature, heart and respiratory frequency and the number of rumen movements) were taken 1 times from the patient group animals and 1 times from the vaccine group animals before vaccination (Control group) and 1st, 3rd, 7th and 14th days after vaccination (respectively Vaccine-1 group, Vaccine-2 group, Vaccine-3 group and Vaccine-4 group) for hematological and biochemical analyses. It was observed that the average values of all clinical parameters between the patient group and other groups were statistically significantly different (P<0.05). In terms of the average values of serum AST and CK-MB enzyme activities, the intergroup differences are statistically unimportant (P>0. The levels of serum cTn-I and CK are significantly high (P<0.05) compared to other groups, while the LDH levels in the patient group and the average values in the vaccine-1, vaccine-3 and vaccine-4 groups are significant in the group difference P<0.05 level. As a result, it has been found that shepherd disease significantly affects the levels of clinical, hematological and cardiovascular enzyme activities and vitamins A, C and E and MDA. It is also determined that the vaccine applications are not on a statistical level, but affect all parameters. Therefore, it has been found that vitamin A, C and E, especially in the treatment of patients and in protective vaccines, will be beneficial with the vaccination.

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