Özet:

Primite 20 WP (PIP) containing 20% Pyridaben is used as acaricide and insecticide. In this study, the cytotoxic and genotoxic effects of PIPs have been studied using the root growth, mitotic index (MI), chromosomal abnormalities (KA) and DNA damage in the Allium main-telofaz and comet cells. The concentration value (EC50) that reduces the growth of the root ends of the PIP by 50% compared to the negative control group was found at 50 ppm with the Allium root growth inhibition test. A. Belt roots are exposed to three different concentrations of PIP (25, 50 and 100 ppm), distillated water (negative control) and methyl methane sulfonate (MMS, 10 ppm, positive control) for 24, 48, 72 and 96 hours. PIP has demonstrated cytotoxic effects by statistically reducing root growth and MI, by statistically increasing the damage to KA (destroyed main-telophase, thin chromosome, ligament, bridge and poliploid) and DNA. PIPs should be used carefully and the sito-genotoxic effects should be studied with other toxicology test systems.