Özet:

Pemphigus vulgaris is a chronic autoimmune disease characterized by blistering of the skin and mucosa. Most commonly, the disease begins in the oral mucosa and spreads to the other mucous membranes and skin. The frequency of genital tract involvement in pemphigus vulgaris is rare. When the skin is not involved, the diagnosis may be difficult. After clinical and histopathologic examinations, pemphigus vulgaris was diagnosed at a 46 year old woman who had erosion and ulseration in oral mucosa for 20 years and in genital region for 10 years This case was presented to emphasize that pemphigus vulgaris which may be confirmed easily by histopathologic examination should be kept in mind in the differential diagnosis of oral and genital ulcers which do not respond to treatment.

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