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Amaç: Bu çalışmada sistemik inflamasyon ile ilişkili bir marker olduğu gösterilen; Nötrofillenfosit oranı (NLR), platelet-lenfosit oranı (PLR), ortalama trombosit hacmi (MPV) ve Eritrosit dağılım hacmi (RDW) ile akut pankreatitin (AP) başvuru anındaki ciddiyetini gösteren Ranson kriteri ile aralarındaki ilişkinin gösterilmesi amaçlanmıştır. Gereç ve Yöntem: Ocak 2017 ile Kasım 2018 tarihleri arasında AP tanısı ile takip eden hastaların verilerine retrospektif olarak ulaşıldı. 82 biliyer ve 15 nonbiliyer olmak üzere toplam 139 hasta çalışmaya alındı. Hastaların ilk başvuru anında bakılan hemogram ve biyokimyasal parametreleri, yaşları, cinsiyetleri, ko-morbiditeleri ve yatış süreleri kaydedildi. İlk başvuru anında bakılan Ranson Kriterlerine göre skoru < 3 ve skoru ≥ 3 pozitif olanlar olmak üzere 2 gruba ayrıldı ve bu gruplar karşılaştırıldı. Bulgular: AP tanısı ile takip edilen 139 hastanın 75 (%54)’i erkek, 64 (%46)’ü kadındı. Hastaların 113’ü Ranson kriterlerine göre 3’ün altında 26’sı ise 3 ve üzerindeydi. Ortalama yaş hafif AP grubunda 61±20 yıl, şiddetli AP grubunda ise 70±13 yıldı. MPV (P< 0.001) ve NLR (P< 0.001) değerleri gruplar arasında anlamlı olarak farklı saptandı. Korelasyon analizinde; NLR ile ranson skoru arasında pozitif korelasyon saptandı (r= 0,253 p<0,01). Yapılan Lineer Regresyon analizi sonucunda, NLR ve PLR’nin AP şiddetini göstermede bağımsız prediktör oldukları bulundu. Sonuç: Sistemik inflamasyonu gösteren çalıştığımız parametrelerden NLR, AP’nin şiddetini belirlemede basit ve güvenilir bir gösterge olarak kullanılabilir
Purpose: This study has been shown to be a marker associated with systemic inflammation; it is intended to demonstrate the relationship between the Ranson criteria, which indicates the severity at the moment of application of the neutrophylenphosate rate (NLR), the platelet-lenphosate rate (PLR), the average volume of thrombocytes (MPV) and the volume of erythrosite distribution (RDW). Tools and Methods: The data of patients followed by AP diagnosis between January 2017 and November 2018 was reached retrospective. A total of 139 patients, including 82 scientists and 15 non-scientists, were taken to study. The first application of the patients was recorded in the hemogram and biochemical parameters, age, gender, co-morbidities and periods of pregnancy. The first application was divided into 2 groups, with score < 3 and score ≥ 3 positive, according to the Ranson Criteria, and these groups were compared. Results: 75 (54%) of 139 patients followed with AP diagnosis were male and 64 (46%) female. According to Ranson criteria, 113 of the patients were below 3 and 26 were below 3 and above. The average age was 61±20 years in the light AP group and 70±13 years in the severe AP group. The values of MPV (P< 0.001) and NLR (P< 0.001) were significantly different between the groups. The correlation analysis found a positive correlation between NLR and ranson score (r=0.253 p<0.01). The Linear Regression analysis found that NLR and PLR were independent predictors in showing AP strength. Result: From the parameters we work to indicate systemic inflammation, NLR can be used as a simple and reliable indicator in determining the severity of AP
Objective: In this study we have shown that there is a marker associated with systemic inflammation; The aim of this study was to determine the relationship between neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), mean platelet volume (MPV) and Erythrocyte distribution volume (RDW) and Ranson Criteria showing the severity of acute pancreatitis (AP) at the time of presentation. Methods: The data of the patients who were diagnosed with AP between January 2017 and November 2018 were retrospectively obtained. A total of 139 patients (82 biliary and 15 nonbiliary) were included in the study. Hemogram and biochemical parameters, age, gender, co-morbidities and duration of hospitalization were recorded. According to the Ranson Criteria used at the time of admission score < 3 and score ≥ 3 positive and these groups were compared. Results: Of the 139 patients diagnosed with AP, 75 (54%) were male and 64 (46%) were female. 113 of the patients were divided into two groups according to the Ranson criteria. The mean age was 61 ±20 years in the mild AP group and 70 ±13 years in the severe AP group. MPV (P <0.001), NLR (P <0.001) values were significantly different between the groups. In the correlation analysis; there was a positive correlation between NLR and ranson score (r = 0.253 p <0.01). Linear regression analysis showed that, NLR and PLR were independent predictors of acute pancreatitis. Conclusion: NLR can be used as a simple and reliable indicator in determining the severity of AP.
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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