Özet:

Intraoperative blood loss is one of the important complications of radical prostatectomy. Appropriate perioperative risk stratification may reduce the possibility of intraoperative blood transfusion. In this study, we aimed to reveal the risk factors that may cause bleeding. 180 patients who were diagnosed with prostate cancer by conventional transrectal ultrasonography biopsy (TRUS-Bx) and underwent retropubic radical prostatectomy (RP) were included in our study. The relationship between the mean blood loss during the operation and the clinical and pathological findings of the patient was examined. Factors that could affect the amount of bleeding and predict the amount of bleeding before the operation were tried to be revealed. The time between TRUS-Bx and RP was statistically significantly longer in patients with a large amount of bleeding (p=0.005). When the level of peroperative bleeding was compared with the TRUS-Bx and RP ISUP scores, both TRUS-Bx and RP ISUP values were statistically significantly higher in patients with high bleeding (>845 cc) (respectively; p=0.024, p<0.001). A 1-unit increase in the TRUS-Bx ISUP score was associated with an increase of 100.04 cc in the amount of peroperative bleeding. In the logistic regression analysis, the most important predictor for the amount of perioperative bleeding was RP ISUP grade (p=0.003). In high-stage patients, bleeding occurs more during the operation. In patients with an ISUP grade and a high biopsy tumor percentage, more careful dissection may reduce the amount of perioperative bleeding. It should be kept in mind that the cancer stage may be higher than the biopsy pathology in patients with a large amount of intraoperative bleeding.

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