Abstract:

Purpose: Primary central nervous system (SSS) lymphoma, a rare form of non-Hodgkin lymphoma (NHL), is defined as a high degree B cell neoplasm of the aggressive extranodal SSS. The incidence of SSS lymphoma has increased in recent years. He has a bad forecast. This study aims to evaluate the clinical, pathological, immunochemical and radiological characteristics of patients diagnosed with primary SSS lymphoma in the literature accompany. The primary SSS lymphoma diagnosis between May 2011 and January 2017 was patologically verified in 10 patients retrospective examination. Results: 7 of 10 patients with SSS lymphoma (70%) were female 3 (30%) were male. The average age of all patients when diagnosed was 59.1±13.98. The most common settlement; 8 patients (80%) were basal ganglia area, and 3 patients (30%) had multiple intrakranal masses. 8 patients (80%) had a sterotox brain biopsy, 2 patients (20%) had a cranyotomy le tumor resection. 10 of all patients with non-Hodgkin B cell lymphoma (100%) were diffuse large B cell lymphoma. In all cases, diffuse and strong positive for CD20 was observed. There was no insufficiency in any patient. Result: Primary SSS lymphoma with poor forecast is often observed over the age of 55. Diffuse is a large B-cell lymphoma subtype and is a basal ganglia regional settlement site.

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Abstract:

Purpose: Primary central nervous system (CNS) lymphoma, a rare form of non-Hodgkin's lymphoma (NHL), is defined as high-grade B cell neoplasm of aggressive extranodal CNS. The incidence of CNS lymphoma has been increasing in recent years. In general, it has a poor prognosis. The aim of this study is to evaluate the clinical, pathological, immunohistochemical and radiological features of patients with primary CNS lymphoma in the light of literature. Materials and methods: Between May 2011 and January 2017, 10 patients with pathologic confirmation of primary CNS lymphoma were retrospectively reviewed. Results: Of 10 patients with CNS lymphoma, 7 (70%) were female and 3 (30%) were male. The mean age of all patients at diagnosis was 59.1±13.98 years. The most common settlements; eight patients (80%) had basal ganglia and 3 patients (30%) had multiple intracranial masses. Sterotaxic brain biopsy was performed in 8 patients (80%) and tumor resection was performed by craniotomy in 2 patients (20%). All of the patients with non-Hodgkin B cell lymphoma had diffuse large B cell lymphoma in 10 (100%). All cases had diffuse and strong positivity for CD20. None of the patients had immunodeficiency. Conclusion: Primary CNS lymphoma with a poor prognosis is frequently seen over 55 years of age. Diffuse large B-cell lymphoma is the most common subtype and basal ganglia is the most common site.