Özet:

Graves’ disease is an autoimmune thyroid disorder. Concurrent Graves' disease with primary thyroid malignities has been at an increasing frequency. The aim of this study is to investigate the prevalence of primary thyroid malignities among thyroidectomy specimens with Graves' disease examined in our department. Methods: The slides of forty patients, which underwent thyroidectomy due to Graves' disease, were re-evaluated in between 2010 and 2016. Results: 11 of 40 thyroidectomy specimens (27.5%) had primary thyroid malignancy. All malignancies were papil lary carcinoma. The prevalence of malignancy was significantly higher in cases of Graves' disease with macroscopic or microscopic nodules than in Graves' patients without nodules (p<0.05). Conclusion: This study also showed that the Graves' disease with nodule had more risk of thyroid malignancy. The patients with concurrent Graves' disease and thyroid nodule should be carefully examined clinically, radiologically, and pathologically for thyroid cancer.

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