Özet:

Diffusion-based magnetic resonance imaging (MRG) is a MRG management based on the principle of measuring the movements associated with the diffusion of water molecules in tissues. Hepatocellular carcinoma (HSK) is a primary malignant tumor found in the liver, and it is very important for curative treatment to be distinguished from other injury in the early stages. In this study, we aimed at exploring the effectiveness of diffusion MRG in distinguishing HSK from other common hepatic focal lesions such as metastasis, colangiocarcinoma and focal nodular hyperplasia (FNH). Methods: Histopathologically, the diagnosis of HSK, metastasis, colangiocarcinoma and FNH was made by a retrospective scan of the diffusion MRG images of a total of 157 patients, with apparent diffusion coefficient (ADC). By comparing the ADC values statistically, it was assessed whether the ADC values contribute to the diagnosis, in particular when distinguishing HSK from other injury. Results: The average ADC values were measured at 836,6 ± 182,4 x10-6 mm2/s in the 38 HSK cases we included in our study, 801,4 ± 239,4 x10-6 mm2/s in the 22 colangiocarcinoma cases, 923,7 ± 279,0 x10-6 mm2/s in the 77 metastasis cases and 1202,9 ± 139,3 x10-6 mm2/s in the 20 FNH cases. There was a significant statistical difference between the ADC values of HSK and FNH. Between HSK and other focal lesions, there is no statistically significant difference. The result: when distinguishing HSK from FNH, ADC values make an additional contribution to the diagnosis, while when distinguishing HSK from cholangiocarcinoma and metastasis, ADC values make an additional contribution to the diagnosis.

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