Özet:

In this study, the effects of aflatoxin B1 (AFB1) given to the eggs on the embryonic development of thlbia and its proximal growth plate were determined by histological and histometric methods. A total of 1024 eggs; control, delinip-kapatrlan, solvent. 2.5ng AFB( / egg, 5ng AFB, / egg, 7.5ng AFB, / egg, 10ng AFB^ egg, 15ng AFB, / egg. 17.5 ng AFB was equal to 10 groups, including t/ egg and 20 ng AFB,/ egg. Test solutions were injected through the air chambers and before incubation. On the 13th, 15th, 17th, 19th and 21st days of the incubation, the first and second weeks after the exit of the cattle were taken examples of tibia from 5 animals from each group. Tibia samples, after the soft tissues were removed, were treated in the sensitive shell and determined by length with the digital shell. Following, it was blocked in the paraffin by following routine histological techniques. The cuts of the 6 pm thickness taken from the blocks were painted with triple painting, hematoxylene-eosine, Schmorl's pickro-lionine method, Alizarin red-S and Von Kossa metotlany. The AFB was determined to be significantly lower than the average thumb length and weight of the given group (P<0.05) than the controlled, delineated and solvent groups. Preparatlann light prepared from the same tissues in microscopic studies, the growth plate of the reserve, proliferative and hypertrophic zones, AFB, in the given groups (P<0.05) was studied significantly; the transitional zone, in particular, 17. It was noted that 5 ng and 20 ng/AFB were significantly expanded (P<0.05) in the egg groups. The result was that the AFBj found in the egg undermines the embryonic development of the embryo’s skeletal system and that these effects in its characteristics are evident in the reserve, proliferative and hlpertrophic zone.

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