Abstract:

Despite the current treatment options, there is no significant increase in the treatment compliance of patients with bipolar disorder. In those with chronic disease, adherence to treatment is an important factor affecting recovery. Non-adherence to treatment is generally explained by “lack of insight” in psychiatric disorders. Adherence to treatment also affects the way the patient's family and himself perceive the disease. Medication compliance is adversely affected by patients with insufficient social support, lack of knowledge about the disorder, dysfunctional attitudes in their families, and fear of stigma. Three main items related to non-compliance with drug therapy were identified in the studies. Patient-related factors; age, gender, marital status, substance use, psychotic disorder, personality disorder, earnings related to patient role, factors related to illness; insufficient insight, insufficient information on long-term drug use, the disease becoming chronic, lack of information about the disease, stigma, disease acceptance/rejection, drug-related factors; improvement or no signs of improvement, side effects, and concerns about drug addiction. Among these substances, the most known are drug-related side effects. In individuals with bipolar disorder, drug non-compliance decreases the quality of life and increases the rate of hospitalization. It also causes high care costs and mortality, depressive episodes and suicides. Identifying and eliminatingthe factors that cause treatment non-compliance will increase treatment compliance and reduce treatment costs and the number of hospitalizations.

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