Özet:

AimAlthough meperidine and tramadol are widely used after cesarean sections in many centers, comparative clinical studies are rare. Therefore, we designed a prospective randomized study to compare tramadol and meperidine following elective cesarean births.MethodsFrom September 2009 to May 2010, 101 women who had elective cesarean section were included in the study. The women were allocated into meperidine and tramadol groups. There were 51 women in meperidine group and 50 women in tramadol group. Both agents were used in 50mg doses at the first hour following the termination of the anesthesia.Visual analogue scale was used for pain scoring at the 1st,4th,8th,12th and 24th hours following the initial analgesic dose. If the pain scores were higher than 4, an additional dose of 25 mg was supplied for each agent.All the participants were observed for nausea, vomiting and other side effects during visual analogue scale scorings.Means and standard deviations were calculated for demographic data. The parameters of visual analogue scale scores, additional dose requirements and side effects were compared in the two groups by using independent variations Student t test. p value 0.05).In the comparison of the parameters of visual analogue scale pain score, nausea, vomiting, itching and the requirements for additional doses, the two groups did not show significant differences from each other at 1st,4th,8th,12th and 24th hours (p>0.05), although tramadol group had higher pain scores and meperidine group had higher nausea, vomiting and itching rates.ConclusionIntramuscular tramadol and meperidine have similar analgesic efficacy and side effects following elective cesarean births. Both agents can be substituted for each other and additional dose requirements are higher in the early postoperative hours.

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