Özet:

Purpose: The aim of this study was to evaluate the influence of Bifidobacterium lactis and Hindiba inulin on feeding intolerance and weight gain in premature babies. Material and Methods: Eighty nine premature babies with the diagnosis of feeding intolerance were enrolled in the study. Study group had Bifidobacterium lactis (5x109 CFU) + Hindiba inulin (900 mg) (Maflor) per oral, while control group did not have any medication for feeding intolerance.  Results: B. lactis ve H. inulin was continued for a mean of  10 days. Time of full enteral feeding and time of starting oral feeding were longer in study group and this was statistically significant. Although lower birth weight, longer total parenteral nutrition duration, later starting of oral feeding and longer duration for start of full enteral feeding in the study group, there was no statistical difference in weights of the babies at discharge time when compared with the control group. When the groups were compared according to weight gain, study group gained more weight and it was statistically significant. Although necrotizing enterocolitis was not significantly different between groups, babies in the study group diagnosed as in Stage 1 and did not worsen. 33.3% of the babies in the control group progressed to Stage 2.   Conclusion: Probiotics and prebiotics might have positive effects due to higher weight gain especially >1500 g birth weight infants and not advancing necrotizing enterocolitis in the study group having B. Lactis and H. inulin.

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