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Amaç: Bu çalışmada şizofreni tanılı hastalarda D vitamini, Pozitif ve Negatif Sendrom Ölçeği skorları, antipsikotik kullanımı ve sosyodemografik verilerin metabolik sendrom ile ilişkisinin gösterilmesi amaçlanmıştır. Gereç ve Yöntem: Retrospektif dosya tarama esasına bağlı bu çalışmaya Çukurova Üniversitesi Tıp Fakültesi Ruh Sağlığı ve Hastalıkları Anabilim Dalı yataklı servisinde sağaltım görmüş 31’inde metabolik sendrom tanısı olan 119 şizofreni tanılı hasta dahil edilmiştir. Hastaların sosyodemografik verileri, hastalık yılı, yatış sayısı, Pozitif ve Negatif Sendrom Ölçeği skorları, vitamin D kan düzeyleri, HDL, trigliserit, glukoz, HBa1c, arteriyel kan basıncı değerleri, bel çevresi, vücut kitle indeksi ölçümleri incelenmiştir. Bulgular: Çalışmaya dahil edilen hastaların 63’ü kadın, 56’sı erkektir. Hastaların 63’ünde vitamin D düzeyi düşüklüğü saptanmıştır. MS tanısı olanlar ve olmayanları arasında HDL, arteriyel kan basıncı, açlık kan glukozu, trigliserit, bel çevresi, vücut kitle indeksi değerlerinin analizinde anlamlı farklılık saptanmıştır. Bu değerler National Cholesterol Education Programme Adult Treatment Panel III metabolik sendrom tanı kriterleri olduğu için lojistik regresyon analizine dahil edilmemiştir. Basit lineer regresyon ve lojistik regresyon analizi ile metabolik sendrom tanısı olan grupta olmayanlara göre hastalık yılı ve hasta yaşları anlamlı olarak yüksek, D vitamini düzeyleri anlamlı olarak düşük saptanmıştır. Sonuç: Bu çalışmada metabolik sendrom riskini arttıran faktörlerden değiştirilebilir olan vitamin D kan düzeyine dikkat edilmesi gerektiği gösterilmiştir.
Purpose: In this study, patients diagnosed with schizophrenia were intended to show the scores of vitamin D, positive and negative syndrome scale, antipsychotic use and the association of sociodemographic data with metabolic syndrome. Tools and Methods: Retrospective file screening is linked to this study, including 119 patients diagnosed with schizophrenia, diagnosed with metabolic syndrome in 31 who were provided in the Department of Mental Health and Diseases of the University of Çukurova Medical School. Patients’ sociodemographic data, year of disease, number of deposits, positive and negative syndrome scale scores, vitamin D blood levels, HDL, triglyceride, glucose, HBa1c, arterial blood pressure values, back circle, body mass index measurements have been studied. Results: 63 of the patients involved in the study are women and 56 are men. In 63 patients, a low level of vitamin D was detected. Between those diagnosed with MS and those not diagnosed, a significant difference has been found in the analysis of the values of HDL, arterial blood pressure, hunger blood glucose, triglyceride, back circle, body mass index. These values have not been included in the logistical regression analysis because they are the criteria for the diagnosis of metabolic syndrome in the National Cholesterol Education Programme Adult Treatment Panel III. Basic linear regression and logistical regression analysis and non-diagnosed metabolic syndrome in the group, the age of the disease and the patient’s age are significantly high, the levels of vitamin D are significantly low. This study has shown that vitamin D levels in the blood, which can be altered by factors that increase the risk of metabolic syndrome, should be observed.
Purpose: The aim of this study was to determine the relationship between vitamin D levels, Positive and Negative Syndrome Scale scores, the use of antipsychotics and sociodemographic data in metabolic syndrome in patients with schizophrenia. Materials and Methods: A total of 119 patients with schizophrenia who were treated at inpatients clinics of Çukurova University Faculty of Medicine Department of Psychiatry were included in this retrospective study. Thirtyone of 119 patients with schizophrenia were diagnosed with metabolic syndrome. Sociodemographic data, duration of disorder, number of hospitalizations, Positive and Negative Syndrome Scale scores, vitamin D blood levels, HDL, triglyceride, glucose, HBa1c, arterial blood pressure, waist circumference, body mass index were measured.. Results: Of the patients included in the study, 63 were female and 56 were male. Vitamin D levels were lower in 63 patients. Significant differences were found in HDL, arterial blood pressure, fasting blood glucose, triglyceride, waist circumference, body mass index values among those with and without metabolic syndrome. These values are not included in the logistic regression analysis because they are metabolic syndrome diagnostic criteria for the National Cholesterol Education Program Adult Treatment Panel III. Simple linear regression and logistic regression analysis showed that the disease year and patient ages were significantly higher and vitamin D levels were significantly lower in the metabolic syndrome group. Conclusion: It has been shown that vitamin D blood level should be taken into account in the factors that increase the risk of metabolic syndrome..
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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