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D vitamini yağda çözünen bir vitamin olup güneş ışığına cevap olarak sentezlenir. Aktif form 1, 25 OH 2D'dir. Kemik sağlığı, serum kalsiyum ve fosfor düzeyleri üzerinde önemli bir rol oynar. Son epidemiyolojik çalışmalar düşük D vitamini düzeyleri ve birçok hastalık arasındaki ilişkiyi göz önüne sermiştir. Düşük D vitamini düzeyleri erişkinlerde osteomalazi, otoimmün ve bulaşıcı hastalıklar, diabetes mellitus, artmış düşme ve kırık riski, kanser, hipertansiyon ve kardiyovasküler hastalıklar ile ilişkilidir. Burada D vitamini fizyolojisi, metabolizması, eksikliği ve takviye için yeni öneriler literatürde yayınlanan yeni bulgular dikkate alınarak gözden geçirilmiştir
Vitamin D is a vitamin that is soluble in fat and is synthesized as a response to sunlight. The active form is 1, 25 OH 2D. It plays an important role in bone health, serum calcium and phosphorus levels. Recent epidemiological studies have taken into account the relationship between low vitamin D levels and many diseases. Low levels of vitamin D in adults are associated with osteomalysis, autoimmune and infectious diseases, diabetes mellitus, increased risk of fall and break, cancer, hypertension and cardiovascular diseases. Here, new recommendations for vitamin D physiology, metabolism, deficiency and supplementation have been reviewed taking into account the new findings published in the literature.
Vitamin D, a fat-soluble vitamin, synthesised in response to sunlight. The active form is 1, 25- OH 2D. It plays an important role in bone health, serum calcium and phosphate levels. Recent epidemiologic studies have observed relationships between low vitamin D levels and multiple disease states. Low vitamin D levels are associated with osteomalacia in adults, autoimmune and infectious diseases, diabetes mellitus, increased risk of fall and fractures, cancer, hypertension and cardiovascular diseases. Here vitamin D physiology, metabolism, deficiency and new recommendations for supplementation are reviewed by taking into consideration new findings published in the literature
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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