Özet:

Chronotype and sleep disorders are both considered risk factors for chronic autoimmune diseases. However, there is lack of knowledge with regard to chronic inflammatory bowel disease and chronotype patterns. Therefore, we investigated the chronotype and sleep quality in patients with ulcerative colitis and Crohn's disease. Methods: Patients with Crohn's disease and ulcerative colitis were prospectively enrolled in the study. Chronotype and sleep quality were assessed using the Mornings Evenings Questionnaire and Pittsburg Sleep Quality Index scores and the results were compared to healthy controls. Results: A total of 134 patients were included in the study. Of these patients 41 had Crohn's disease, 49 had ulcerative colitis and 44 were healthy controls. Eveningness was more common in patients with Crohn's disease and ulcerative colitis compared to controls (12.2%, 18.4%, 0%, respectively, p<0.001). However, there was no difference in chronotype based on the disease activity or between Crohn's disease and ulcerative colitis. In terms of sleep quality, inflammatory bowel disease was found to be an independent risk factor for sleep disorders (OR= 1.5; 1.04-2.33 95% CI; p=0.02). Conclusion: Eveningness was more common in patients with Crohn's disease and ulcerative colitis compared to controls. In addition, inflammatory bowel disease seems to be a significant risk factor for sleep disorders.