Özet:

Objectives: The study aimed to evaluate the remineralizing effect of hemp on initial enamel caries lesions. Materials and method: Initial caries lesions were created on twenty-eight intact enamel samples with demineralization solution (pH=4.5) in a shaking incubator for 72 hours at 37⁰C. Samples were divided into 4 groups (n=7) ((1) experimental toothpaste containing hemp (H) (SPC Kozmetik), (2) hemp oil (HO), (3) Sensodyne Repair and Protection toothpaste (S) (GSK), (4) Control (no treatment)). The agents were applied using a pH-cycle model for seven days. All agents were kept on the surface of samples for 2 minutes and then applied for 1 minute using an electric toothbrush (Oral-B Test Drive (Genius)). Samples were evaluated with microhardness, FluoreCam, and DIAGNOdent Pen. Data were statistically analyzed with ANOVA and Kruskal Wallis H tests (p<0.05). Results: According to fluorescence and microhardness evaluations, the remineralization effect was similar in all treatment groups, except for hemp oil (p<0.01). Groups S (288.86±9.63), and H (284.86±10.41) showed significantly higher microhardness values compared to HO (238.57±10.89) (p<0.001). According to FluoreCam data, lesion size decreased in S (-1.83) and H (-1.07), while an increase was observed in HO (0.75). According to DIAGNOdent Pen data, the mineral increase in S (-8.42±1.18) and H (-8.29±1.03) was significantly higher than in HO (-3.57±2.06) (p<0.001). Conclusions: Herbal toothpaste containing hemp (H) demonstrated a similar remineralization effect to Fluor and Novamin-containing toothpaste (S).

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