Özet:

Aim: Hypoxic ischemic encephalopathy (HIE) is one of the most important reason of morbidity and mortality in neonates. This study was aimed to review the etiology, clinical-laboratory features and mortality rate of neonates with HIE.Material and Method: Sixty-three full-term babies with HIE admitted to the Erzurum Nenehatun Obstetric and Maternity Hospital Neonatal Intensive Care Unit between March 2007 and March 2008 were evaluated retrospectively.Results: HIE was diagnosed in 6.1% of all patients observed in our unit in this period. There were 20 females (31.7%) and 43 males (68.3%). The mean gestational age was 38.8±1.4 weeks and the mean birth weight was 3265±561 gram. The ratio of neonates delivered by cesarean section was 23.8%, and by spontaneous vaginal delivery was 76.2%. The etiologic factors for hypoxic ischemic encephalopathy were intrapartum 58.8% and antepartum 12.8%. The most frequently affected organs were liver (58.7%), lung (54%) and kidney (42.9%), except central nervous system. The ratio of neonates who developed seizures within the first week of life was 61.9%. According to modified Sarnat and Sarnat staging, 17 (27%) patients were in Stage I, 27 (42.8%) in Stage II and 19 (30.2%) in Stage III. The mean hospitalization time was 11.9±12.9 days. The mortality rate was 27% (17), while 63% of neonates has been discharged.Conclusion: HIE still continues to be an important health issue in Neonatal Intensive Care Units, especially in the eastern Turkey, despite advances in diagnosis and treatment

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