Abstract:

Several contemplated ‘scaffold platforms’ have been reported recently for the feasible treatment of various disorders and diseases. These engineered scaffold platforms base on two main factors: stem/progenitor cells and biomaterial scaffolds for the regeneration of many diseased and injured tissues and/or organs. There are so many limitations for end-stage organ failure treatment ways. Thus, future advance in tissue engineering will depend on improving new scaffolding methods. Currently instead of regenerate whole organ, decellularization techniques used for obtained native extracellular matrix (ECM) scaffold platform are one of the most successful techniques. In the light of this information, in this paper we review the current status of scaffold platform technologies; ‘decellularization methods’ for various tissues and stem cell therapy strategies for tissue engineering.

Keywords: