Özet:

CaP-based bioceramic materials are widely used in orthopedic applications. β-tri-calcium phosphate (β-TCP) is a bioresorbable member of the CaP-based compounds and can be implemented as putty, coating, powders, granules, etc. depending on the implantation area. β-TCP is usually produced with wet chemical synthesis systems. However, long synthesis durations, processes with multiple steps, and difficulties in controlling the process parameters yield the researches to develop novel production methods. Recently, the microwave-assisted synthesis technique has drawn attention due to its advantages such as being a shorter and more practical experimental procedure. In this study, β-TCP powders were fabricated via the microwave-assisted synthesis method. Ca and P source solutions were prepared, and following their reaction microwave radiation was applied. The obtained product was centrifuged to separate the precipitate, and then this wet part was dried, and finally calcined at 900°C. In this way, Ce3+ and SeO3-2 doped β-TCP powders, which may show antibacterial properties and induce bone regeneration were achieved. Chemical phase analysis with X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Energy Dispersive Spectroscopy (EDS) observations to investigate the microstructure and elemental mapping, immersion in the Simulated Body Fluid (SBF) for 14 days at 37°C to determine the bioactivity behavior, and bacteria interaction studies by using Staphylococcus aureus (S. aureus, ATCC 25923) to evaluate the antibacterial activity of the synthesized powders were done within characterization. Formation of the CaP-based precipitates on the surfaces of the powders depending on immersion in 1X SBF solution showed the bioactive character of the products. Moreover, a reduction in the number of bacterial colonies proved that the ion-doped powders exhibited antibacterial properties.

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