Özet:

Primary gastric tumors are encountered more frequently than metastatic tumors. The gastric metastasis of clear cell renal cell carcinoma (CCRC) is very rare. We herein report a case of gastric metastasis of CCRC. A sixty-year-old man patient underwent a radical nephrectomy and received adjuvant chemotherapy. Pulmonary metastasis occurred at the second-year follow-up, and interferon alpha-2a was used for relapse. The Computed Tomography examination of the patient presented with dyspepsia two years after pulmonary metastases revealed 11 mm thickness in the (along) gastric wall. Endoscopic examination was suggestive of a neuroendocrine tumor. Histopathologic evaluation of endoscopic biopsies showed tumoral cell groups in a solid pattern composed of clear, vacuolated cytoplasm. These tumor cells were positive for RCC, PAX8 CD-10, Vimentin, and immunohistochemistry findings were similar to the initial tumor at diagnosis. Finally, the patient was diagnosed with CCRC's gastric metastasis and treated with a multi-targeted receptor tyrosine kinase inhibitor.

Anahtar Kelimeler: