Abstract:

Obesity is a complex disease and general health problem that is defined as excess fat storage in the tissue. Research in our country obesity prevalence as 12-22%. Obesity has been shown to be associated with various rheumatism diseases and inflammation. The aim of this study is to investigate the pre-obesity in the rheumatoid diseases and the relationship with the activity of the disease. Method: New osteoartritis (OA), rheumatoid arthritis (RA), ankylosan spondylitis (AS), systemic lupus eeritamatosus (SLE), fibromyalgia (FM), gut, Behcet disease (BH), vasculitis, polymyalgia romatika (PMR), Sjögren syndrome (SS), family Mediterranean fever, polymyositis and systemic sclerosis (SSc) diagnosed 1064 patients were included in the study. Patients’ age, gender, disease activity scores, laboratory and clinical findings have been recorded. The findings: Obesity incidents were identified as 4.5 % in RA, 3.2 % in SLE, 1.6 % in AS, 40 % in OA, 11.2 % in FM, 19.7 % in gutta, 1.8 % in BH, 15 % in vasculite, 13.7 % in PMR, 8 % in SS and 8.3 % in SSc. A statistically strong relationship between obesity and OA has been found. The activity scores of the disease were statistically significantly higher compared to those who were not obese in obese FM patients (p<0,001). While the rate of obesity is low in inflammatory rheumatism diseases, there is no connection between obesity and disease activity. Results: The latest studies have shown a relationship between obesity and inflammation, but our study has shown an interesting relationship between obesity and OA and FM patients, but there is no relationship between inflammatory rheumatism diseases. The relationship between OA and obesity can be explained by mechanical factors, but more comprehensive research is needed to explain the relationship between FM and other inflammatory rheumatism diseases and obesity.

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