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Parkinson Hastalığında Retina Sinir Lifi Tabakası ve Makula Kalınlığının Değerlendirilmesi
2018
Journal:  
Dicle Tıp Dergisi
Author:  
Abstract:

Amaç: Parkinson hastalarını retina sinir lifi tabakası (RSLT) ve makula kalınlıkları yönünden incelemek ve sağlıklı kontrol grubu ile karşılaştırmak Yöntem: Parkinson tanısı alan yaş ortalaması 69,2±8,2 yıl olan 25 hasta ve sistemik hastalık öyküsü bulunmayan yaş ortalaması 67,2±7,1 yıl olan 19 hasta göz bulguları açısından değerlendirildi. Hastalara Optik Koherens Tomografi (OKT) ile RSLT ve makula kalınlık ölçümleri yapıldı. Gruplar elde edilen veriler açısından Student t testi ile karşılaştırıldı. Bulgular: İnferior kadran RSLT Parkinson grubunda 133,1±19,3 μm, kontrol grubunda ise 145,1±19,6 μm olarak ölçüldü. İnferior kadran RSLT’deki bu incelme istatistiksel olarak anlamlı bulundu (p=0,049). Diğer kadran RSLT ve makula kalınlıklarında gruplar arası fark tespit edilmedi.  Sonuç: Çalışmamızda Parkinson hastalarında inferior kadran RSLT kalınlığında azalma tespit ettik. Parkinson hastalarında retinadaki dopamin miktarında meydana gelen azalma ganglion hücre kaybına yol açarak RSLT kalınlığında incelmeye neden olabilmektedir.

Keywords:

Evaluation of the retina nerve lifi layer and macula thickness in Parkinson's disease
2018
Journal:  
Dicle Tıp Dergisi
Author:  
Abstract:

Purpose: Study and compare Parkinson patients in the direction of the retina nerve fiber layer (RSLT) and macula thickness with the healthy control group Method: The average age of the patients diagnosed with Parkinson was 69.2±8.2 years and the average age of the patients with a systemic disease history was 67.2±7.1 years. Patients received optical coherence tomography (OKT) with RSLT and macula thickness measurements. The groups were compared with the Student t test in terms of the data obtained. The inferior square was 133.1±19.3 μm in the RSLT Parkinson group and 145.1±19.6 μm in the control group. This review in the lower scale RSLT found statistically meaningful (p=0,049). There was no difference between the group in the RSLT and macula thicknesses of the other square. The result: In our study, we found a decrease in the thickness of RSLT of the inferior square in Parkinson’s patients. The decrease in the amount of dopamine in the retina in patients with Parkinson may lead to the loss of ganglion cells, causing the examination of the RSLT thickness.

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Dicle Tıp Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 1.608
Cite : 3.094
2023 Impact : 0.081
Dicle Tıp Dergisi